

This route was established by a "building block" strategy, in which the researchers integrated chemical and biological catalytic modules to utilize high-density energy and high-concentration CO 2 in a biotechnologically innovative way. To address this issue, scientists at the Tianjin Institute of Industrial Biotechnology (TIB) of the Chinese Academy of Sciences (CAS) designed a chemoenzymatic system as well as an artificial starch anabolic route consisting of only 11 core reactions to convert CO 2 into starch. Designing novel routes other than plant photosynthesis for converting CO 2 to starch is an important and innovative S&T mission and will be a significant disruptive technology in today's world. Strategies for the sustainable supply of starch and use of CO 2 are urgently needed to overcome major challenges of mankind, such as the food crisis and climate change. The theoretical energy conversion efficiency of this process is only about 2%. This process involves about 60 biochemical reactions as well as complex physiological regulation.

At present, it is mainly produced by crops such as maize by fixing CO 2 through photosynthesis. Starch is the major component of grain as well as an important industrial raw material.

The new route makes it possible to shift the mode of starch production from traditional agricultural planting to industrial manufacturing, and opens up a new technical route for synthesizing complex molecules from CO 2.
